THE GENUS AS, A POTENTIAL SOURCE OF ANTICANCER AGENT: AN UPDATED REVIEW

Abstract

On the list of the world's most significant health problems, cancer rates are high. As a consequence, cancer
 treatment is a global priority. A cell may acquire malignant characteristics by learning how to avoid
 apoptosis. Defects in regulating apoptotic pathways enable cancer cells to become chemoresistant,
 highlighting the need to develop new anti-apoptotic drugs to combat the disease. Apoptosis can be induced
 by inhibiting anti-apoptotic factors or by activating pro-apoptotic molecules. However, the adverse side
 effects of chemotherapy have prompted researchers to investigate whether medicinal plants could replace
 chemotherapy in cancer treatment. Pistachios have antioxidant, antifungal, antimicrobial, and anticancer
 properties, among many other pharmacological benefits. The ability of pistachios to inhibit tumor growth
 is supported by data indicating that they do so by modulating multiple apoptotic pathways in tumor cells.
 This article introduces pistachios and discusses their potential anticancer effects, mainly targeting apoptosis
related pathways